Does Coffee Reduce the Risk of Multiple Sclerosis? A Look at the Evidence

Interesting research for those, like us, who love coffee. It is still difficult to know the true benefit at this point, or whether a meaningful effect really exists, but a meta-analysis is a strong study design and worth noting. Recent research examining multiple studies suggests that people who drink coffee may have a lower risk of developing multiple sclerosis (MS). A systematic review and meta-analysis of eight studies found that coffee drinkers were about 22% less likely to develop MS compared with those who did not drink coffee. Individual study results varied. Some suggested a stronger protective relationship, others found little difference, and a few even reported higher risk among coffee drinkers. However, when the data were combined, the overall findings suggested that coffee consumption may be associated with potential neuroprotective effects (Rastkar et al., 2025).

Rastkar, M., Jannatalipour, E., Mohamadi, A., Ghajarzadeh, M., & Ghajarzadeh, M. (2025). Coffee consumption and risk of multiple sclerosis (MS): A systematic review and meta-analysis. Neurodegenerative Disease Management, 1–7. https://doi.org/10.1080/17582024.2025.2587546